Preview match : Cologne coach Frank Schafer says his side cannot afford to lose, even if their opponents are Bayern Munich.
Schafer's calculations for how his side can avoid relegation do not take any slip-ups into consideration, which is why he is demanding three points at the Mungersdorfer Stadion.
"There is no such thing as a game in which you have nothing to lose," he said.
"We are right in the midst of a relegation battle and we cannot say that we have a game now which does not count.
"Such a game provides us with a big chance to send out a positive signal as a team."
Former Bayern goalkeeper Michael Rensing has strengthened the Cologne rearguard since he arrived at the club this winter and he will be particularly motivated against his old team.
"He has been the backbone of our team for our first three games this year and we are certainly happy with the impression he has made," Schafer told Sport1.de.
"He had a difficult time (at Bayern) and searched for a new beginning here.
"He is now here writing a new chapter, and that should be a positive one."
Lukas Podolski also comes up against his former club, this time wearing the armband as Cologne captain.
Bayern's new captain is Philipp Lahm, who was given the armband after Mark van Bommel's sale to AC Milan.
His first game in charge was a success with a 3-1 win at Werder Bremen last weekend and he is enjoying the new responsibility.
"I love to be the leader," he told the Bild newspaper. "But I don't want to be a dictator.
"That doesn't work nowadays. I would like to be a captain who is open to discussions on any level, a good person for my team-mates, the coach, the board and the public to talk to."
Arjen Robben is a doubt for Bayern due to a cold, but Franck Ribery could make a surprise return to the squad.
He was able to train fully yesterday, three weeks after suffering a knee injury, and could find a place on the bench.
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